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Topoisomerase II inhibitors, which include mitoxantrone, have been affiliated with the event of secondary acute myeloid leukemia and myelosuppression.Drug Interactions Mitoxantrone and its metabolites are excreted in bile and urine, but It's not at all regarded if the metabolic or excretory pathways are saturable, could possibly be inhibited or ind

RUNX1 is often a grasp transcription element that regulates the expression of various genes needed for hematopoiesis. Studies implied that the RUNX1Achievable new methods for the analysis and treatment of AML. (A) The identification of super enhancers depending on the different regulating things, DNA mutations and chromatin standing could offer new